Association between Medication Possession Ratio (MPR) in Type 2 Diabetes Mellitus Patients and Glycosylated Haemoglobin (HbA1c) in Klinik Kesihatan Tendong, Kelantan: A Preliminary Study

Authors

  • Zahari HL Biological Sciences Programme, School of Distance Education, Universiti Sains Malaysia, 11800 Minden, Pulau Pinang, Malaysia
  • Abdul Ghani AA Tendong Health Clinic, 17030 Pasir Mas, Kelantan
  • Amirah Hurzaid Biological Sciences Department, School of Distance Education, USM, 11800 Minden, Penang

Keywords:

MPR, MRCI, Age, HbA1c outcomes, diabetes mellitus

Abstract

Background: Diabetes mellitus is highly prevalent in Malaysia, affecting a sizeable portion of the population. The country faces a growing burden, with an estimated prevalence rate of around 18.3%. Several factors contribute to the non-adherence of diabetes medication including demographic factors, complex medication regimens, inadequate communication with healthcare providers and cultural beliefs. Identifying the major factor that led to non-adherence on medication should be prioritized to achieve good glycaemic control with a HbA1c target of less than 7% for most diabetic patients. Objectives: This study aims to identify the factors affecting patients’ Medication Possession Ratio (MPR) and how MPR is associated with HbA1c outcomes from retrospective data collection. Method: A retrospective study was conducted on a selected sample of 300 individuals who attended Klinik Kesihatan Tendong from May to June 2023. Secondary data on MPR was extracted from the Pharmacy Information System (PhIS) while HbA1c outcomes were obtained from the National Diabetes Registry database. Results: The study successfully demonstrated significant association between MPR with HbA1c outcomes in the patients. Patients with good adherence accounted for the majority of the study population (N=80.5%) with HbA1c levels below 7. Conclusion: The use of MPR as a tool to determine medication adherence of patients was proven to have significant association with HbA1c outcomes.

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Published

2025-12-30

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Journal of Biomedical and Clinical Sciences