A Rare Case of Castleman Disease of the Neck: Unicentric Type with Plasma Variant

Authors

  • Harridas Manickam Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia
  • Suhaimi Yusuf Department of Otorhinolaryngology, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia
  • Ahlam Naila Kori Department of Hematology, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia
  • Azlina Abd Rahman Department of Pathology, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia
  • Norhidayah Jalani Department of Pathology, Hospital Tengku Ampuan Afzan, 25100 Kuantan, Pahang, Malaysia
  • Irfan Mohamad Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia

Keywords:

Castleman disease, lympho proliferative disorder, non-cancerous, plasma cell

Abstract

Castleman disease (giant or angio follicular lymph node hyperplasia) is an uncommon lymphoproliferative disorder which is localised to single lymph node (unicentric) or multiple lymph node level systemically (multicentric). It is a very rare disorder characterised by non-cancerous growths. The most common sites of this are mainly thorax (mediastinum or lung hilum) and abdomen. It rarely occurs in the head and neck area. We report a 17-year-old girl who had left neck swelling for 5 years. The excised mass was histopathologically confirmed as Castleman of a rare plasma cell variant, treated with adjuvant radiotherapy. Follow-up after one year showed no recurrence.

Author Biographies

  • Harridas Manickam, Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia

    OTORHINOLARYNGOLOGY DEPARTMENT 

    MEDICAL OFFICER UD 48

  • Irfan Mohamad, Department of Otorhinolaryngology-Head & Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Health Campus, 16150 Kota Bharu, Kelantan, Malaysia
    Professor (Otorhinolaryngology-Head & Neck Surgery)

References

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Published

2023-05-31

Issue

Section

Journal of Biomedical and Clinical Sciences